tag:blogger.com,1999:blog-9870114.post3979432210913325143..comments2024-03-10T08:41:32.400+00:00Comments on VIRTUAL GRAND ROUNDS IN DERMATOLOGY 2.0: A Diagnostic DilemmaHumane Medicine Huihttp://www.blogger.com/profile/07113291188306363130noreply@blogger.comBlogger5125tag:blogger.com,1999:blog-9870114.post-58430727313086813082015-07-19T11:07:42.136+00:002015-07-19T11:07:42.136+00:00From Barry Ladiainzki (Dermatology Resident in Chi...From Barry Ladiainzki (Dermatology Resident in Chicago): “I can tell you from working with a national expert on lymphomas that with an atypical lymphoid infiltrate biopsy sans positive gene rearrangement studies. He would not treat as CTCL and likely just use topical steroids and monitor.<br />He would also rarely use radiation for small lesions such as this (even B-Cell Lymphoma) and try topical nitrogen mustard, interferon or MTX, etc. before going to anything stronger."<br />Humane Medicine Huihttps://www.blogger.com/profile/07113291188306363130noreply@blogger.comtag:blogger.com,1999:blog-9870114.post-83348650233727492242015-07-14T20:34:05.370+00:002015-07-14T20:34:05.370+00:00Henry Foong of Ipoh Malaysia wrtoe: "tough on...Henry Foong of Ipoh Malaysia wrtoe: "tough one. cases nowadays are increasingly more of lymphomas nowadays. One has to be well verse with IHC as most cutaneous lymphomas need such special studies. i think this could be a CD20 positive T celll lymphoma ."Humane Medicine Huihttps://www.blogger.com/profile/07113291188306363130noreply@blogger.comtag:blogger.com,1999:blog-9870114.post-66932064887376001512015-07-14T13:51:26.037+00:002015-07-14T13:51:26.037+00:00Andrew Carlson from Albany Medical Center (NY) wro...Andrew Carlson from Albany Medical Center (NY) wrote: "'s likely a cutaneous marginal zone lymphoma.<br /><br />In order to DX confidently, you have to the lymphoma work up/pane for cutaneous B cell lymphomas.<br /><br />Any tick bite history, Borrelia positive serology, and/or response to to antibiotic (doxycylcine) therapy?"Humane Medicine Huihttps://www.blogger.com/profile/07113291188306363130noreply@blogger.comtag:blogger.com,1999:blog-9870114.post-24275439908543475262015-07-14T13:49:02.431+00:002015-07-14T13:49:02.431+00:00Khalife Sharquie from Baghdad, Iraq wrote: "T...Khalife Sharquie from Baghdad, Iraq wrote: "The clinical picture is that of B cell lymphoma although pseudolyphoma might resemble thiscondition.Screening for visceral involvement is essential.strong topical steroid is enough and follow up for any further progression is mandatory."Humane Medicine Huihttps://www.blogger.com/profile/07113291188306363130noreply@blogger.comtag:blogger.com,1999:blog-9870114.post-82425187864250228812015-07-14T09:51:55.279+00:002015-07-14T09:51:55.279+00:00Larry Gibson of the Mayo Clinic wrote: "In re...Larry Gibson of the Mayo Clinic wrote: "In reference to the this patient, I think another consideration is CD4positive small/medium cell pleomorphic T cell lymphoma. These are often solitary and patients are OW healthy. There are typically a lot of CD20 B cells and molecular studies may be negative. The stains are PD1, CXCL13 and Bcl6 can be done looking for coexpression by the T cells.<br />These lymphomas can be treated by excision or excision followed by localized radiotherapy.Humane Medicine Huihttps://www.blogger.com/profile/07113291188306363130noreply@blogger.com